What Does "In Remission" Mean?
Remission doesn't always mean cured. Learn the difference between partial remission, complete remission, and NED — and what they mean for your outlook.
OncoNav Medical Team·April 26, 2025·5 min read
## What Remission Means
Remission means that the signs and symptoms of cancer have decreased — or in some cases, are no longer detectable. It is good news, but it has an important distinction from being cured.
## Types of Remission
### Partial Remission (PR)
The cancer has responded to treatment and shrunk significantly (usually defined as ≥30% reduction in tumor size) but has not disappeared entirely. Treatment typically continues.
### Complete Remission (CR) / Complete Response
No cancer is detectable on scans, in blood tests, or on physical exam. This is often called being in "complete remission."
**Important:** Complete remission does not always mean cured. Some cancers can return even after achieving complete remission.
### NED (No Evidence of Disease)
Similar to complete remission. No cancer is detectable with current testing methods. This is the term commonly used after surgery when all visible tumor has been removed. (See our dedicated NED article for more.)
## Remission vs. Cure
Cure means the cancer will not return. Remission means the cancer is currently undetectable or significantly reduced.
Oncologists are often reluctant to use the word "cure" because:
- Cancer can recur years or even decades later
- Current tests cannot detect every cancer cell
- "Cured" is sometimes declared after a long period (often 5 years) without recurrence
For some cancers (like Hodgkin lymphoma or early-stage testicular cancer), achieving complete remission after treatment is functionally equivalent to cure in most patients.
For others (like many stage 4 solid tumors), complete remission is achieved less commonly, and even when it is, recurrence is more likely.
## How Remission Is Assessed
- **CT or PET scans** — imaging to measure tumor size and metabolic activity
- **Blood tests** — tumor markers (like PSA for prostate, CA-125 for ovarian, CEA for colorectal)
- **Bone marrow biopsy** — for blood cancers like leukemia
- **Liquid biopsy / ctDNA** — emerging tool to detect residual cancer DNA in the bloodstream
## After Remission: Surveillance
Once in remission, you enter a surveillance phase — regular check-ups, scans, and blood tests to watch for signs of recurrence. Frequency depends on cancer type and risk of recurrence.
It is completely normal to feel anxious during this phase. Many patients describe fear of recurrence as one of the hardest aspects of life after cancer treatment.
⚠️ Medical Disclaimer:This article is for informational and educational purposes only. It is not medical advice and does not replace the guidance of your oncologist, physician, or qualified healthcare provider. Every patient's situation is unique — symptoms, treatment decisions, and urgent care needs vary based on your individual diagnosis, treatment plan, and medical history. Always consult your oncologist or care team regarding any symptoms, concerns, or questions about your care — including decisions about whether to seek emergency care or stay home. Do not delay seeking professional medical attention based on information in this article. If you are experiencing a medical emergency, call 911 immediately.
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